Announcing PiAware 3.8.1!

It’s actually main memory as /run in in memory.

You haven’t describe what else you have set up besides piaware, so impossible to guess what the issue is.
You can check /run for big files i suppose:

sudo reboot
sudo apt install ncdu

Then when the problem occurs again:

sudo ncdu /run

Could also be some program using lots of memory.

Honestly if you don’t have a clue, better to reimage.

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