It could help, yes. The Uputronic LNA is more sensitive to saturation than the tripple-filtered LNA from SDR-RTL. That said, it’s not super-sensitive, just not as robust as the tripple-filtered LNA.
The Uputronic LNA is hardware-only. No settings can be made, just different kind of filters that can be applied between the antenna and the LNA to filter out unwanted parts of the radio spectrum.
Different filters do that in different ways and can be quite cheap (filters from AliExpress etc can be good or total rubbish) or really expensive (cavity filters designed for 1090Mhz).
The FA filter is probably the most cost-effective filter you can buy for this application. It usually solves the problem with interference. It would be my first choice when cables, connectors etc has been ruled out as the source of problem.